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Index > Protein center > Slc12a1(Gene name) > Rat
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  • Slc12a1 (Gene name),
  • Solute carrier family 12 member 1 (Protein name ),  S12A1_RAT from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Slc12a1(Nkcc2);
    Protein name:
    Solute carrier family 12 member 1;
    Alternative:
    Kidney-specific Na-K-Cl symporter;Bumetanide-sensitive sodium-(potassium)-chloride cotransporter 2;
    Organism:
    Rat (Rattus norvegicus). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Electrically silent transporter system. Mediates sodium and chloride reabsorption. Plays a vital role in the regulation of ionic balance and cell volume.
    Subcellular Location:
    Membrane Multi-pass membrane protein
    Protein Attributes:
    Sequence length:
    1095
    Sequence:
    50:
    MSVNIPSNSV | PSGASRFQVH | VINEGHGSGA | AMSDSTDPPH | YEETSFGDEA | 
    100:
    QNRLKISFRP | GNQECYENFL | QTGETAKTDT | TFHAYDSHTN | TYYLQTFGHN | 
    150:
    TMDAVPKIEY | YRNTGSVSGP | KVNRPSLQEI | HEQLAKNVAV | APGSADRVAN | 
    200:
    GDGMPGDEQA | ENKEEDVTGV | VKFGWVKGVL | VRCMLNIWGV | MLFIRLSWIV | 
    250:
    GEAGIGLGVI | IIGLSVVVTT | LTGISMSAIC | TNGVVRGGGA | YYLISRSLGP | 
    300:
    EFGGSIGLIF | RFANAVRVAM | YVVGFAETVV | DLLKESDSMM | VDPTNDIRII | 
    350:
    GSITVVILLG | ISVAGMEWEA | KAQVILLVIL | LIGIANFFIG | TVIPSNNEKK | 
    400:
    SRGFFNYQAS | IFAENFGPSF | TEGEGFFSVF | AIFFPAATGI | LAGANISGDL | 
    450:
    EDPQDAIPRG | TMLAIFITTV | AYIGVAICVR | ACVVRDATGS | MNDTVVSGMN | 
    500:
    CNGSAACGLG | YDFSRCQHEP | CQYGLMNNFQ | VMSMVSGFGP | LITAGIFSAT | 
    550:
    LSSALASLVS | APKVFQALCK | DNIFKGLQFF | AKGYGKNNEP | LRGYFLTFVI | 
    600:
    AMAFILIAEL | NVIAPIISNF | FLASYALINF | SCFHASYAKS | PGWRPAYGIY | 
    650:
    NMWVSLFGAI | LCCAVMFVIN | WWAAVITYVI | ELFLYIYVTY | KKPDVNWGSS | 
    700:
    TQALSYVSAL | DNALELTTVE | DHVKNFRPQC | IVLTGGPMTR | PALLDITHAF | 
    750:
    TKNSGLCICC | EVFVGPRKLC | VKEMNSGMAK | KQAWLMKNKI | KAFYAAVAAD | 
    800:
    CFRDGVRSLL | QASGLGRMKP | NTLVIGYKKN | WRKAPLSELE | NYVGIIHDAF | 
    850:
    DFEIGVVIVR | ISQGFDISPV | LQVQDELEKL | EQERLALEAA | IKDNDCEEGK | 
    900:
    GGIRGLFKKA | GKLNITKPAP | KKDSNISTIQ | SMHVGEFNQK | LVEASAQFKK | 
    950:
    KQGKGTIDVW | WLFDDGGLTL | LIPYILTLRK | KWKDCKLRIY | VGGKINRIEE | 
    1000:
    EKISMASLLS | KFRIKFADIH | IIGDINIKPN | KESWKVFEEM | IEPYRLHESH | 
    1050:
    KDLTTAEKLK | RESPWKITDA | ELEAVKEKSY | RQVRLNELLQ | EHSRAANLIV | 
    1095:
    LSLPVARKGS | ISDLLYMAWL | EILTKNLPPV | LLVRGNHKNV | LTFYS
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    String:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Rat Solute carrier family 12 member 1
    Cat.:
    E0312h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Rat Solute carrier family 12 member 1
    Cat.:
    E0312r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Rat Solute carrier family 12 member 1
    MSDS:
    Please sign in first.
    ELISA Kit for Rat Solute carrier family 12 member 1
    Cat.:
    E0312m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat Solute carrier family 12 member 1
    Cat.:
    U0312m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat Solute carrier family 12 member 1
    Cat.:
    U0312r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat Solute carrier family 12 member 1
    Cat.:
    U0312h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Rat Solute carrier family 12 member 1
    MSDS:
    Please sign in first.
    Polyclonal Antibody for Rat Solute carrier family 12 member 1
    Cat.:
    P0312Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat Solute carrier family 12 member 1
    Polyclonal Antibody for Rat Solute carrier family 12 member 1
    Cat.:
    P0312Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat Solute carrier family 12 member 1
    Cat.:
    P0312Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Rat Solute carrier family 12 member 1
    Monoclonal Antibody for Rat Solute carrier family 12 member 1
    Monoclonal Antibody for Rat Solute carrier family 12 member 1
    Monoclonal Antibody for Rat Solute carrier family 12 member 1
    Protein for Rat Solute carrier family 12 member 1
    Protein for Rat Solute carrier family 12 member 1
    Protein for Rat Solute carrier family 12 member 1
    Protein for Rat Solute carrier family 12 member 1

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    References
    1. 1.
      "Molecular cloning, primary structure, and characterization of two members of the mammalian electroneutral sodium-(potassium)-chloride cotransporter family expressed in kidney."
      Gamba G. , Miyanoshita A. , Lombardi M. , Lytton J. , Lee W.S. , Hediger M.A. , Hebert S.C.
      J. Biol. Chem.269:17713-17722(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      strain: Sprague-Dawley.
      tissue: Kidney.
    2. 2.
      "Regulation of the renal-specific Na+-K+-2Cl- co-transporter NKCC2 by AMP-activated protein kinase (AMPK)."
      Fraser S.A. , Gimenez I. , Cook N. , Jennings I. , Katerelos M. , Katsis F. , Levidiotis V. , Kemp B.E. , Power D.A.
      Biochem. J.405:85-93(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION AT SER-126
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